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BIOLOGY
Asked by Sarah

What are the two layers of the basement membrane, and what makes each layer?

The Basement Membrane is a sheet of extracellular material that separates the epithelial cells from the connective tissue. It consists of two layers, the Basal Lamina and the Reticular Lamina. 1. The Basal Lamina is made of a mixture of collagen, laminin (glycoprotein), entacin (glycoprotein) and pelican (heparin sulphate glycoprotein). Under the microscope we can distinguish 2 layers of Basal Lamina, the Lamina lucida(electron lucent) and the Lamina densa (electron dense). 2.The Lamina reticularis (or Reticular lamina) is usually thicker than the Basal lamina and is mainly made of reticular fibres, as the name suggests.

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